Into Great Silence without VGLUT3
نویسندگان
چکیده
The vesicular glutamate transporters VGLUT1 and VGLUT2 fill synaptic vesicles with glutamate, an essential prerequisite for glutamatergic transmission in the CNS. In contrast, the third isoform, VGLUT3, is not confined to glutamatergic neurons, and its function has remained enigmatic. In this issue of Neuron, Seal et al. show that mice lacking VGLUT3 are profoundly deaf and exhibit nonconvulsive seizures.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 57 شماره
صفحات -
تاریخ انتشار 2008